d -Ribose as a Contributor to Glycated Haemoglobin
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چکیده
منابع مشابه
d-Ribose as a Contributor to Glycated Haemoglobin
Glycated haemoglobin (HbA1c) is the most important marker of hyperglycaemia in diabetes mellitus. We show that d-ribose reacts with haemoglobin, thus yielding HbA1c. Using mass spectrometry, we detected glycation of haemoglobin with d-ribose produces 10 carboxylmethyllysines (CMLs). The first-order rate constant of fructosamine formation for d-ribose was approximately 60 times higher than that ...
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ژورنال
عنوان ژورنال: EBioMedicine
سال: 2017
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2017.10.001